Accession Number : ADA126870

Title :   Retrograde Amnesia in Rats, Produced by Electron Beam Exposure.

Descriptive Note : Final rept. Jul-Sep 82,

Corporate Author : SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TX

Personal Author(s) : Wheeler,Thomas G. ; Hardy,Kenneth A. ; Blick,Dennis W.

Report Date : FEB 1983

Pagination or Media Count : 33

Abstract : It has been demonstrated that electron beam exposure produces retrograde amnesia (RA). RA production was evaluated using a single trial avoidance task across a 10,000 dose range for 10 microseconds, 1 microsecond, and 0.1 microseconds pulsed exposures. The dose-response curve obtained at each pulse duration showed significant RA production. The most effective dose range was 0.1-10 rads at a dose rate of 1 million rad/sec. Our conclusion was that the RA effect might be due to sensory system activation which provided a novel stimulus that masked previous stimuli (produced RA).

Descriptors :   *EXPOSURE(GENERAL), *RATS, *ELECTRON BEAMS, *AMNESIA, EXPERIMENTAL DATA, STRESS(PHYSIOLOGY), TEST METHODS, AVOIDANCE, LEARNING, DOSE RATE, MENTAL ABILITY, IONIZING RADIATION, RADIATION DOSAGE, RADIATION EFFECTS, ULCERS, SUBLETHAL DOSAGE.

Subject Categories : PSYCHOLOGY
      ANATOMY AND PHYSIOLOGY
      RADIOBIOLOGY

Distribution Statement : APPROVED FOR PUBLIC RELEASE

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