Accession Number : AD0163662

Title :   Toxic Chemical Vaccines.

Descriptive Note : Patent,

Corporate Author : OFFICE OF THE SECRETARY OF THE ARMY WASHINGTON D C

Personal Author(s) : Cuculis,John J. ; Meyer,Howard G. ; Sim,Van M. ; Sternberger,Ludwig A.

Report Date : 15 FEB 1972

Pagination or Media Count : 3

Abstract : The invention relates to a new composition of matter and method useful as a vaccine prophylactic means to protect mammals against poisoning by an anticholinesterase composition such as isopropyl methylphosphonofluoridate, diisopropyl phosphonofluoridate, diethyl-p-nitrophenyl phosphate, ethyl phosphorodimethylamidocyanidate, and tetraethyl pyrophosphate. The vaccine is the product resulting from the reaction of a carrier with a compound selected from a benzene substituted with an organophosphate or organophosphonate and a diazonium, carboxyl, amino acid, amide, isocyanate, or isothiocyanate.

Descriptors :   (*VACCINES, *CHOLINESTERASE INHIBITORS), (*PATENTS, VACCINES), ORGANIC PHOSPHORUS COMPOUNDS, NITRILES, TOXICITY, POISONING, IMMUNITY

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE