Accession Number : AD0163887

Title :   1,3-BIS(4-Chlorophenyl)-2-Propen-1-One Guanylhydrazone Hydrochloride and Analogs Thereof Useful as Antimalarials.

Descriptive Note : Patent,

Corporate Author : OFFICE OF THE SECRETARY OF THE ARMY WASHINGTON D C

Personal Author(s) : Henry,David W.

Report Date : 10 APR 1973

Pagination or Media Count : 4

Abstract : The patent describes the preparation of three analogous compounds, 1,3-bis(4-chlorophenyl)-2-propen-1-one guanylhydrazone hydrochloride, 1,3-bis(4-chlorophenyl)-2-buten-1-one guanylhydrazone hydrochloride, and 1,3,3-tris(4-chlorophenyl)-2-propen-1-one guanylhydrazone hydrochloride. The compounds are useful in the prevention and treatment of malaria.

Descriptors :   (*PATENTS, ANTIMALARIALS), (*GUANIDINES, *ANTIMALARIALS), (*HYDRAZONES, ANTIMALARIALS), SYNTHESIS(CHEMISTRY), AROMATIC COMPOUNDS, HALOGENATED HYDROCARBONS, CHLORINE COMPOUNDS

Subject Categories : Pharmacology
      Organic Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE