Accession Number : AD0163889

Title :   S-Substituted Thiosulfuric Acid Derivatives and Preparation Thereof.

Descriptive Note : Patent,

Corporate Author : OFFICE OF THE SECRETARY OF THE ARMY WASHINGTON D C

Personal Author(s) : Bauer,Ludwig

Report Date : 08 MAY 1973

Pagination or Media Count : 5

Abstract : The patent describes antiradiation compounds comprising a molecule which includes a component with antiradiation properties linked to a component with substantial lipid solubility. The seven compounds are S-4(N-substituted carboxamidinium)methyl5 thiosulfuric acids (Bunte salts) having the general formula (-)O3SSCH2C(=NH2(+)NHR and hydrolysis products thereof, wherein R represents bi- and tricyclic aliphatic ring systems. The antiradiation effectiveness is reported.

Descriptors :   (*PATENTS, RADIOPROTECTIVE AGENTS), (*THIOSULFATES, RADIOPROTECTIVE AGENTS), (*ORGANIC SULFUR COMPOUNDS, *RADIOPROTECTIVE AGENTS), SYNTHESIS(CHEMISTRY), POLYCYCLIC COMPOUNDS, LIPIDS, SOLUBILITY, ORGANIC NITROGEN COMPOUNDS

Subject Categories : Pharmacology
      Organic Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE