Accession Number : AD0255943

Title :   THE EFFECT OF IRRADIATION ON AUTOLOGOUS SKIN TRANSPLANTS

Corporate Author : ALBERT EINSTEIN MEDICAL CENTER PHILADELPHIA PA

Personal Author(s) : ELKIN,MILTON ; SALVIONI,DANIELE

Report Date : APR 1961

Pagination or Media Count : 1

Abstract : Localized irradiation in large enough dosage prejudices successful autologous skin transplantation in the rabbit. It appears that the deleterious effects of irradiation in this respect are first manifested in the graft itself; at higher doses, damage to the recipient site prevents takes. At the qualities of irradiation used in these experiments (HVL 0.31 mm Al and 2.2 mm Al), 2200r to the donor skin prevented successful grafting whereas this dose to the recipient site showed no significant diminution in per cent of graft takes as compared to control levels. Administration of cysteine intravenously just before irradiation afforded partial protection to the donor skin. (Author)

Descriptors :   *RADIATION EFFECTS, *SKIN(ANATOMY), *TRANSPLANTATION

Distribution Statement : APPROVED FOR PUBLIC RELEASE