Accession Number : AD0258937

Title :   THE GROWTH AND DIETARY PATTERN OF RATS ON SELF-SELECTION DIETS FOLLOWING WHOLE-BODY IRRADIATION

Corporate Author : NAVAL RADIOLOGICAL DEFENSE LAB SAN FRANCISCO CALIF

Personal Author(s) : KONISHI,F.

Report Date : 22 MAY 1961

Pagination or Media Count : 1

Abstract : The apparent ability of rats to voluntarily select a dietary according to the needs of the body was utilized in a study to detect possible metabolic derangements subsequent to a dose of 375 rad whole-body X-irradiation. The animals were allowed free choice selections of various foodstuffs offered in separate containers and the relative amounts of food intake as well as body weights were measured daily. The majority of the rats were able to select diets adequate enough to support normal growth. Upon irradiation at the level employed, rats fed a basal pre-mixed diet lost significantly more body weight than similarly treated rats selecting their own diet. In the over-all pattern, the proportion of casein selected progressively increased whereas that of sucrose decreased subsequent to the irradiation. The selections of yeast and corn oil remained essentially the same. On the third day only, after irradiation, the intake of minerals increased to over 5 times the pre-irradiation level . The selection and intake of casein returned to pre-irradiation levels by the third day while the total caloric intake of irradiated rats on basal and self-selected diets returned to normal levels by the 5th day. (Author)

Descriptors :   *BODY WEIGHT, *DIET, *GROWTH(PHYSIOLOGY), *NUTRITION, *RADIATION EFFECTS, CASEIN, CORN, FOOD, METABOLISM, MINERALS, RATS, SELECTION, SUCROSE, YEASTS

Distribution Statement : APPROVED FOR PUBLIC RELEASE