Accession Number : AD0261758

Title :   EFFECT OF LIPOTROPIC FACTORS ON COLD PHYSIOLOGY

Corporate Author : GEORGE WASHINGTON UNIV WASHINGTON D C

Personal Author(s) : TREADWELL,CARLETON R.

Report Date : APR 1961

Pagination or Media Count : 1

Abstract : George Washington U., Washington, D. C. EFFECT OF LIPOTROPIC FACTORS ON COLD PHYSIOLOGY, by Carleton R. Treadwell. Apr 61, 37p. incl. illus. tables, 15 refs. (Proj. 7952-5) (AAL TR 60-18)Unclassified report DESCRIPTORS: *Physiology, *Exposure, *Diet, *Liver, Tissue (Biology), Muscles, Experimental data, Laboratory animals, Ketones, *Metabolism, Vitamins, *Growth, Stress (Physiology), *Lipids, Blood, Proteins, *Lipoproteins, Nutrition, Cholesterol, Acidosis, Phospholipids. Open-ended Terms: Liver cirrhosis. Several experiments have been carried out to study the lipotropic effect of cold upon fatty livers produced by deficiencies of methyl donors. It was found that at 1 C, diets containing as little as 5% protein and as much as 40% fat did not produce the fatty livers characteristic of these diets when fed at 25 C. It was also found that when animals with fatty livers were maintained at 1 C, there was a marked lipotropic effect without any change in diet composition. Cold also has both curative and preventive lipotropic effects on the triglyceride fraction of the livers of animals receiving diets which will produce cholesterol fatty livers. Other experiments suggest that animals at 1 C undergo an adjustment such that either larger amounts of ketone bodies can be metabolized or fewer ketone bodies are produced. (Author)

Descriptors :   *CONDENSATION TRAILS, *EXPOSURE(PHYSIOLOGY), *GROWTH(PHYSIOLOGY), *LIPIDS, *LIPOPROTEINS, *LIVER, *METABOLISM, *PHYSIOLOGY, ACIDOSIS, BLOOD, CHOLESTEROL, EXPERIMENTAL DATA, KETONES, LABORATORY ANIMALS, MUSCLES, NUTRITION, PHOSPHOLIPIDS, PROTEINS, STRESS (PHYSIOLOGY), TISSUES (BIOLOGY), VITAMINS

Distribution Statement : APPROVED FOR PUBLIC RELEASE