Accession Number : AD0263120

Title :   THE STUDY OF BURN AND WOUND HEALING IN THE ALBINO RAT DEFICIENT IN VITAMINS AND OTHER ESSENTIAL FOOD SUBSTANCES

Corporate Author : TEXAS A AND M UNIV COLLEGE STATION

Personal Author(s) : BROWN,SIDNEY O.

Report Date : JAN 1961

Pagination or Media Count : 1

Abstract : IN A SERIES OF STUDIES COMPARING RADIODENSITOMETRIC TECHNIQUES WITH HISTOLOGICAL METHODS, IT WAS FOUND THAT BONE INCISURES WERE ESSENTIALLY HEALED BY THE END OF 10 WEEKS. However, new bone was thinner than original shaft and somewhat spongy; older, original shaft bone had become thick but less dense with large porous areas. Bone healing in rats fed B-complex deficient diets did not show any severe retardation and was as rapid as in those animals on adequate levels of B-complex vitamin. Burn wounds showed no specific differences in rate of healing for animals on 5, 25, and 100% pyridoxine supplemented diets, nor did rats at these levels show symptoms of deficiency except for decreased size. Rats at 100% pyridoxine level failed to repair as rapidly as those on 5 and 25% levels. Over-all well being and particularly condition of reproductive organs were found to be related to caloric intake of male albino rats. Muscles, bone, and skin remained in youthful condition when animals were on sharply restricted diets, but endocrine and reproductive systems were not retarded in development by insufficient caloric intake. (Author)

Descriptors :   *BURNS(INJURIES), *HEALING, *WOUNDS AND INJURIES, DIET, NUTRITION, PROTEINS, THERAPY, VITAMINS

Distribution Statement : APPROVED FOR PUBLIC RELEASE