Accession Number : AD0268538

Title :   FURTHER STUDIES ON REDUCTION OF X-IRRADIATION MORTALITY OF GUINEA PIGS BY PLANT MATERIALS

Corporate Author : QUARTERMASTER FOOD AND CONTAINER INST FOR THE ARMED FORCES CHICAGO ILL

Personal Author(s) : CALLOWAY,DORIS HOWES ; CALHOUN,W.K. ; MUNSON,A.H.

Report Date : NOV 1961

Pagination or Media Count : 1

Abstract : Exposure to 400 r of whole-body X-irradiation resulted in 97 percent mortality in 10 to 15 days among young male guinea pigs fed a basal diet of bran and oats plus ascorbic acid. Supplementaton with alfalfa or boccoli, for two weeks before irradiation and during 30 days after irradiation reduced mortality and extended survival time. Although supplementation of an adequate purified diet with broccoli or alfalfa promoted superior weight gain, radiosensitivity was unaffected under these conditions. The beneficial effect of green plant supplementation could not be duplicated by feeding a mixture of 48 chemically-defined ingredients patterned upon the composition of broccoli, in conjuncion with the bran-oats diet. The radioprotective agent(s) in alfalfa was water-soluble. (Author)

Descriptors :   *DIET, *RADIATION HAZARDS, *X RAYS, INHIBITION, LABORATORY ANIMALS, RADIATION EFFECTS, SAFETY, SENSITIVITY

Distribution Statement : APPROVED FOR PUBLIC RELEASE