Accession Number : AD0269688

Title :   BIOLOGICALLY ACTIVE STEROID GLYCOSIDES FROM HOLOTHURIANS

Corporate Author : NEW YORK ZOOLOGICAL SOCIETY BROOKLYN

Personal Author(s) : NIGRELLI,ROSS F.

Report Date : DEC 1961

Pagination or Media Count : 1

Abstract : Published reports show that the crude holothurin derived from the Cuvierian tubules of the Bahamian sea-cucumber Actinopyga agassizi has a wide variety of biological properties, including an irreversible blocking action on nerve, interference in the se uential developmental processes of the sea-urchin egg, and inhibition of certain tumors in mice. The published paper appended to this report summarizes the effects of holothurin on various biological systems and also includes a bibliography of the several papers published on this subject. (Author)

Descriptors :   *ECHINODERMATA, *FISHES, *GLYCOSIDES, *MARINE BIOLOGY, *STEROIDS, BIOCHEMISTRY, BIOLOGY, CHEMICAL PROPERTIES, CHEMOTHERAPEUTIC AGENTS, ECOLOGY, INHIBITION, NERVES, TOXICITY

Distribution Statement : APPROVED FOR PUBLIC RELEASE