Accession Number : AD0271474

Title :   CHRONIC EFFECTS OF CONTINUOUS LOW-LEVEL GAMMA RADIATION UPON B VITAMIN REQUIREMENTS

Corporate Author : WESTERN BIOLOGICAL LABS CULVER CITY CALIF

Personal Author(s) : ERSHOFF,B.H. ; GRAHAM,T.M.

Report Date : OCT 1961

Pagination or Media Count : 1

Abstract : IMMATURE MALE RATS WERE FED A HIGHLY PURIFIED DIET CONTAINING LOW, MEDIUM AND HIGH DOSES OF THE B vitamins. A fourth group was fed a natural food stock ration. Animals were exposed for periods up to 17 weeks to gamma irradiation from a Cesium-137/Barium-137 source at levels of 0, 3, 30, 300, and 500 r per week. Average length of survival at the 500 r per week level was significantly longer for rats fed the stock ration than for rats fed the purified diets. No significant dif erence in growth increment, appearance, organ weights or length of survival attributable to differences in B vitamin content were observed among the various groups. General animal activity measured by an open field test decreased with exposure to radiation up to 8 weeks duration while canges in learning ability were noted after 17 weeks. The composition of the diet employed was without significant effect on activity or learning performance on either irradiated or nonirradiated rats. (Author)

Descriptors :   *GAMMA RAYS, *RADIATION EFFECTS, *VITAMIN B COMPLEX, GROWTH(PHYSIOLOGY), LABORATORY ANIMALS, LEARNING, NUTRITION, SURVIVAL(PERSONNEL)

Distribution Statement : APPROVED FOR PUBLIC RELEASE