Accession Number : AD0276434

Title :   MECHANISM OF ADAPTATION TO A THREONINE-DEFICIENT DIET. II. CYTOCHROME OXIDASE AND FATTY ACID OXIDASE ACTIVITIES

Corporate Author : ARCTIC AEROMEDICAL LAB FORT WAINWRIGHT ALASKA

Personal Author(s) : ARATA,DOROTHY

Report Date : OCT 1961

Pagination or Media Count : 1

Abstract : The effect of a threonine deficiency on liver fat levels and cytochrome oxidase activities were observed over a period of 6 weeks in rats fed 9% casein diets containing either 5% or 20% corn oil. Liver fat in the low-fat, threonine-deficient group rose to a peak at two weeks and then decreased by the end of the 6-week experimental period. The activity of cytochrome oxidase was significantly depressed in both threonine-deficient groups, but to a greater extent in the rats fed the low-fat diet. No marked fluctuations with time were observed in this system in any of the three dietary groups. Fatty acid oxidase activity was markedly stimulated in threoninedeficient rats while fat was being mobiled out of the livers. (Author)

Descriptors :   *AMINO ACIDS, *OXIDOREDUCTASES, CYTOCHROME OXIDASE, FATTY ACIDS, LIVER, METABOLISM, STARVATION

Distribution Statement : APPROVED FOR PUBLIC RELEASE