Accession Number : AD0276441

Title :   A THERMAL DILUTION TECHNIQUE FOR ESTIMATING THE CARDIAC OUTPUT IN SMALL ANIMALS

Corporate Author : ARCTIC AEROMEDICAL LAB FORT WAINWRIGHT ALASKA

Personal Author(s) : EVONUK,EUGENE

Report Date : OCT 1961

Pagination or Media Count : 1

Abstract : A thermal dilution method is described for recording time-temperature curves for calculating the cardiac output in the intact small animal. Isotonic saline at normal room temperature served as the dilution indicator. This method depends upon accurate recording of the rates of change in the blood temperature which occur in the arch of the aorta when cool isotonic saline is injected near the right atrium. Reproducibility of duplicate measurements of the cardiac output in five species of small animals was determined and statistically compared. There were no statistically significant differences between the measurements. This thermal dilution method provides a very suitable means of continuous recording of the time-temperature dilution curve for estimating the cardiac output in the intact small animal. (Author)

Descriptors :   *HEART, *PHYSIOLOGY, BLOOD CIRCULATION, BLOOD VOLUME, BODY TEMPERATURE, MAMMALS, MEASUREMENT, STATISTICAL ANALYSIS, TEMPERATURE, TEST METHODS, TIME

Distribution Statement : APPROVED FOR PUBLIC RELEASE