Accession Number : AD0281747

Title :   EFFECT OF ACUTE AND CHRONIC LOW TEMPERATURE STRESS ON SURVIVAL OF MICE CHALLENGED WITH STAPHYLOCOCCUS AUREUS,

Corporate Author : ARCTIC AEROMEDICAL LAB FORT WAINWRIGHT ALASKA

Personal Author(s) : Marcus ,Stanley ; Miya,Fred

Report Date : OCT 1961

Pagination or Media Count : 10

Abstract : Normal and immunized mice were subjected to acute and chronic stress of 2 C ambient temperature. The mice were challenged with varying doses of Staphylococcus aureus, strain Fritchie. Immunization offered significant protection to mice kept at 21 C and to mice that were immunized, challenged and acutely exposed to 2 C in groups. No protection was observed in mice that were immunized, challenged and exposed as individuals to 2 C. Also, immunized mice that were chronically cold exposed at 2 C were not protected against subsequent challenge and showed equivocal mortality ratios compared to the normal controls challenged under the same conditions. (Author) 0

Descriptors :   *HYPOTHERMIA, *STAPHYLOCOCCUS, *STRESS (PHYSIOLOGY), EXPOSURE(PHYSIOLOGY), IMMUNITY, SURVIVAL(PERSONNEL)

Distribution Statement : APPROVED FOR PUBLIC RELEASE