Accession Number : AD0282210

Title :   STUDY AND RESEARCH ON ELECTRONIC SIMULATION OF THE BIOLOGICAL CLOCK.

Descriptive Note : Final rept.,

Corporate Author : ARIZONA UNIV TUCSON

Personal Author(s) : Sage,Andrew P. , Jr. ; Cockrum,E. Lendell

Report Date : MAY 1962

Pagination or Media Count : 81

Abstract : A general review of the literature on the biological aspects of light and temperature in relation to pacemaking is given. Both periodic and random shock effects, including the effects of periods different from twenty-four hours, frequency demultiplication, variation of intensity and duration of shocks, and multiple shocks, are described. The data are translated into a general mathematical model for the biological clock. A hybrid (digital-analog) model for the biological clock is then proposed. The electronic model consists basically of a sequential logic circuit, an analog response computer, and an activity state control. The sequential logic circuit is the basic decision mechanism which determines the changes to be made in activity state on the basis of past and present activity states and external stimuli. The analog portion of the model is used to determine the exact amount of change to be made; the activity state control represents the present activity state and receives all command inputs for state changes. (Author)

Descriptors :   (*RHYTHM), (*BIOLOGY TIME), ANIMALS, LIGHT, TEMPERATURE, ANALOG COMPUTERS, DIGITAL COMPUTERS, SEQUENCES(MATHEMATICS), COMPUTER LOGIC, SWITCHING CIRCUITS, TRIGGER CIRCUITS, AUTOMATION, SIMULATION, THEORY, MATHEMATICAL ANALYSIS, PERIODIC VARIATIONS

Distribution Statement : APPROVED FOR PUBLIC RELEASE