Accession Number : AD0283327

Title :   A STUDY OF BONE CHANGES IN ALBINO RATS SUBJECTED TO LOW INTENSITY COBALT-60 GAMMA RADIATION

Corporate Author : TEXAS WOMAN'S UNIV DENTON

Personal Author(s) : MACK,PAULINE BEERY ; VOSE,GEORGE P. ; BROWN,SIDNEY O.

Report Date : 31 AUG 1962

Pagination or Media Count : 1

Abstract : Young adult male albino rats received 50 r/day of Co-60 gamma radiation for 91 days with results compared with non-irradiated controls. The latter surpassed the irradiated animals in: increase in body weight; skeletal growth; rate of fracture healing; and bone strength. A macrofractionated study was conducted with (A) one group of young adult male albino rats which received 50 r/day of C -60 gamma radiation continuously for 77 days; (b) one group with alterna ing 7-day radiation and rest periods for the sa e length of time; and (c) one group receiving no radiation. The fractionated radiation produced less deleterious effects on certain aspects of skeletal statu than the continuous radiation exposure; and the non-irradiated controls surpasse the two irradiated groups. Quantitative microradiographic techniques were applied to a study of the mechanism of the healing of bone fractures. (Author)

Descriptors :   *BONES, *GAMMA RAYS, *RADIATION EFFECTS, *RADIOBIOLOGY, *RADIOGRAPHY, GROWTH(PHYSIOLOGY), LABORATORY ANIMALS, RADIOACTIVE ISOTOPES, VITAMIN A

Distribution Statement : APPROVED FOR PUBLIC RELEASE