Accession Number : AD0287280

Title :   A MATHEMATICAL MODEL FOR THE DISTRIBUTION OF LENGTHS OF CHROMOSOMAL DEFICIENCIES INVOLVING A SPECIFIC LOCUS

Corporate Author : NEW YORK STATE COLL OF AGRICULTURE ITHACA

Personal Author(s) : THOMPSON,K.H. ; WALLACE,B. ; FEDERER,W.T.

Report Date : DEC 1962

Pagination or Media Count : 1

Abstract : A mathematical model of random two-hit reakage and deficiency s developed for the condtion that the chromosoml segment lost includes an arbitrary but specifc locus. Both a discrete band model and a continuous chromosome model are considered in presenting theoretical distributions for deficiency lengths, deficiency midpoints, and other relted characteristics. he problem of eimating the location of essential loci is discussed for the continuous model. (AUTHOR)A-287 2809N3 +++Mthematical analys for the determination of breaks and chromosomal recombinations in Drosophia melanogaster to eluidate the mechansm of the origin of chromosoal rearrangements.

Descriptors :   *CHROMOSOMES, *MATHEMATICAL ANALYSIS, DROSOPHILIDAE, HISTOLOGY

Distribution Statement : APPROVED FOR PUBLIC RELEASE