Accession Number : AD0288686

Title :   THE EFFECT OF COLD EXPOSURE ON THE SURVIVAL OF MOCE INOCULATED WITH VIABLE OR HEAT KILLED SALMONELLA TYPHIMURIUM

Corporate Author : BRYN MAWR COLL PA

Personal Author(s) : PREVITE,J.J. ; BERRY,L.J.

Report Date : JUN 1962

Pagination or Media Count : 1

Abstract : Identifiers: Salmonella typhimurium. Mice exposed to 5 C show an increased susceptibility to the lethal effects of Salmonella typhimurium, strain SR-11A, heat-killed S. typhimurium, or a relatively avirulent strain of Staphylococcus aureus Giorgio. This increase in susceptibility to infection at low environmental temperatures is masked in infections with a more virulent strain of viable S. typhimurium (SR-11). However, with lower doses of the latter, the 25 C exposed mice are at least temporarily more successful in resisting the lethal effects of the disease. The differences in results between infection with SR-11 and SR-11A may be due to the genetic homogeneity and heterogeneity of the two respective cultures. Metabolic changes responsible for the increased susceptibility of the cold exposed animals remain to be investigated. (Author)

Descriptors :   *DISEASES, *EXPOSURE(PHYSIOLOGY), *SALMONELLA, BODY TEMPERATURE, COMMUNICABLE DISEASES, EPIDEMIOLOGY, HEAT, METABOLISM, MICE, SURVIVAL(PERSONNEL), VIABILITY

Distribution Statement : APPROVED FOR PUBLIC RELEASE