Accession Number : AD0291549

Title :   THE EFFECTS OF A CHEMOSTERILANT ON MALARIA IN MOSQUITOES

Corporate Author : ENTOMOLOGY RESEARCH DIV AGRICULTURAL RESEARCH SERVICE ORLANDO FLA

Personal Author(s) : ALTMAN,ROBERT M.

Report Date : 30 NOV 1962

Pagination or Media Count : 1

Abstract : Studies were conducted to determine the effects of the chemosterilant tepa on Plasmodium gallinaceum in Aedes aegypti. It was demonstrated that holding the mosquitoes on a tepa residue of 10 mg./sq. ft. either immediately before or after they fed on infected chicks caused a reduction in the percentage of mosquitoes that became infected and a reduction in the mean oocyst count. Similar exposures also caused reductions in malaria transmission rates. Other experiments demonstrated that tepa reduced the malaria transmission rates when mosquitoes infected for more than 14 days were held on a tepa residue of 10 mg./sq. ft. Malaria did not develop in 35 of 36 mosquitoes that fed on infected chicks one hour after they were inoculated intraperitoneally with tepa at the rate of 100 mg./kg. Malaria developed in chicks following intramuscular inoculation with blood samples taken from infected chicks one hour after they were inoculated intraperitoneally with tepa. (Author)

Descriptors :   *CHEMOTHERAPEUTIC AGENTS, *MAINTENANCE VEHICLES, CULICIDAE, HEMOSPORIDIA

Distribution Statement : APPROVED FOR PUBLIC RELEASE