Accession Number : AD0292642

Title :   FATTY ACID COMPOSITION OF PLASMA AND LIVER LIPID COMPONENTS AS INFLUENCED BY DIETARY PROTEIN AND CHOLESTEROL IN GROWING CHICKS

Corporate Author : ARMY MEDICAL RESEARCH AND NUTRITION LAB DENVER COLO

Personal Author(s) : LEVEILLE,GILBERT A. ; TILLOTSON,JERRY ANN ; SAUBERLICH,HOWERDE E.

Report Date : 04 SEP 1962

Pagination or Media Count : 1

Abstract : Feeding low protein diets to growing chicks results in elevated plasma cholesterol and glyceride levels, but does not alter the plasma lipid phosphorus levels in the absence of dietary cholesterol. Dietary cholesterol elevated all plasma lipid components regardless of dietary protein level; however, the increases were greater in the low protein fed groups. Dietary cholesterol also significantly increased liver lipid levels, more so in the high protein fed animals. The fatty acid composition of plasma and liver cholesterol esters, glycerides and phospholipids was altered by the dietary treatments employed. Although similar changes were noted in all fractions, the phospholipid and glyceride fractions appeared to be refractive to fatty acid changes as compared to the cholesterol esters. Elevations in plasma cholesterol attributable to either low protein or cholesterol feeding were accompanied by decreased linoleic and arachidonic and increased oleic acid levels. The possible relationship of these alterations to atherosclerosis and abnormal lipid metabolism is discussed. (Author)

Descriptors :   *CHOLESTEROL, *FATTY ACIDS, *LIPIDS, *PROTEINS, BIOCHEMISTRY, BLOOD PLASMA, DIET, LIVER

Distribution Statement : APPROVED FOR PUBLIC RELEASE