Accession Number : AD0293175

Title :   CONTINUING STUDIES ON THE METABOLISM OF FATTY ACIDS AND RELATED SUBSTANCES IN ANIMALS EXPOSED TO COLD

Corporate Author : TUFTS UNIV BOSTON MASS SCHOOL OF MEDICINE

Personal Author(s) : RAPPORT,DAVID

Report Date : DEC 1956

Pagination or Media Count : 1

Abstract : Addition of glucose to the incubation medium has proved to be so effective in reversing the changes in hepatic acetate metabolism that occurred with cold-exposure or fasting or both, experiments to test the effect of intermediates of carbohydrate metabolism were made. The addition of pyruvate to the incubation medium caused pronounced changes in the amount of acetate-C14 incorporated into C14O2, fatty acids and cholesterol by metabolizing liver slices. These slices were prepared from control rats, 1-day cold-exposed rats, 1-day fasted rats, 1-day cold-exposed and 1-day cold-fasted rats. (Author)

Descriptors :   *EXPOSURE(PHYSIOLOGY), *FATTY ACIDS, *METABOLISM, CARBON, CHOLESTEROL, GLUCOSE, LABELED SUBSTANCES, LABORATORY ANIMALS, LIVER, POLAR REGIONS, PYRUVATES, RADIOACTIVITY

Distribution Statement : APPROVED FOR PUBLIC RELEASE