Accession Number : AD0410784

Title :   DEEP HYPOTHERMIA IN THE RAT: STUDIES ON SURVIVAL AND TOLERANCE TO CIRCULATORY ARREST,

Corporate Author : DUKE UNIV DURHAM N C SCHOOL OF MEDICINE

Personal Author(s) : Lesage ,M. A. ; Sealy ,W. C. ; Young,W. G. , Jr

Report Date : FEB 1963

Pagination or Media Count : 12

Abstract : A study was carried out to establish whether or not rats could be regularly carried to deep hypothermia and then rewarmed without an exces sively high mortality rate. A technique for in ducing deep hypothermia is described. Rats were cooled to deep hypothermia and revived in a high enough percentage to permit quantitative esti mates of other experimental situations. Hypoxia during cooling and warming is apparently import ant in the improvement of mortality figures. Circulatory arrest of 60 minutes or less is well tolerated during deep hypothermia. (Author)

Descriptors :   (*HYPOTHERMIA, RATS), (*BLOOD, HYPOTHERMIA), TOLERANCE, SURVIVAL(PERSONNEL), TEMPERATURE, PHYSIOLOGY.

Distribution Statement : APPROVED FOR PUBLIC RELEASE