Accession Number : AD0418268

Title :   GASEOUS TISSUE NITROGEN OF RATS EXPOSED TO SIMULATED ALTITUDE AND HIGH CONCENTRATIONS OF NITROGEN,

Corporate Author : ILLINOIS UNIV CHICAGO COLL OF MEDICINE

Personal Author(s) : Marotta,S.F. ; Marbarger,J.P. ; Robbins,E.F.

Report Date : MAY 1963

Pagination or Media Count : 5

Abstract : One hundred and fifty albino male rats were subjected to 12,000 feet simulated altitude while breathing ambient air (group II) or 100% oxygen (group III) for one-half, two, and four hours. When compared with control animals (group I) gaseous nitrogen was eliminated more rapidly in group III than in group II. Tarance of nitrogen from liver, skeletal muscle, and testis was more rapid, however, when animals were denitrogenated with 100% oxygen at ground level than at altitude. The reverse was observed for splenic nitrogen. Muscular and splenic gaseous nitrogen increased when animals were subjected to 10% oxygen in nitrogen (group IV). These observations suggest that local as well as total circulatory alterations accompany ing either decompression, the breathing of gas mixtures, or both, may affect the rate of denitrogenation. (Author)

Descriptors :   (*NITROGEN, TISSUES (BIOLOGY)), (*TISSUES (BIOLOGY), NITROGEN), (*HIGH ALTI, NITROGEN), RATS, AIR, RESPIRATION, OXY, LIVER, MUSCLES, SEX GLANDS, SPLEEN, MIXTURES, LABORATORY ANIMALS.

Distribution Statement : APPROVED FOR PUBLIC RELEASE