Accession Number : AD0420952

Title :   EVALUATION OF THE EFFECTS OF SUBARACHNOID AND EXTRADURAL BLOCK ON CARDIOVASCULAR FUNCTION,

Corporate Author : WASHINGTON UNIV SEATTLE

Personal Author(s) : Bonica,John J. ; Ward,Richard J. ; Takamura,John

Report Date : OCT 1963

Pagination or Media Count : 7

Abstract : A series of patients who required conduction anesthesia for elective surgery was studied. Intracardiac catheterization via the veins of the arm and intraarterial catheterization were performed in the preoperative period. Control values of cardiac-output and pulmonary shunting were made. The patients were given a low or high spinal anesthetic, as required for the surgical procedure, and the cardiac-output and shunt again determined. The patients who were given an epidural anesthetic had a catheter placed in the epidural space for re-injection purposes. A low epidural block was instituted, cardiac-output and shunt studies made, and the block re-inforced with sufficient anesthetic solution to give a high block. Output and shunt studies were repeated. Results so far on fifteen patients indicate that low spinal has no significant effects on cardiac-output, but high block profoundly depressed the cardiovascular apparatus. Low epidural anesthesia, on the other hand, stimulated the heart, increased the cardiac-output, and was associated with a greater drop in peripheral resistance than spinal. Increasing the level of the epidural decreased the cardiac-output a small amount, but this was still significantly above the control level. (Author)

Descriptors :   (*CARDIOVASCULAR SYSTEM, ANESTHESIA), (*ANESTHESIA, SPINAL COLUMN), SURGERY, MEDICAL RESEARCH, PHYSIOLOGY), LUNG, BLOOD CIRCULATION, CARDIOGRAPHY, BLOOD PRESSURE, ARMY RESEARCH

Distribution Statement : APPROVED FOR PUBLIC RELEASE