Accession Number : AD0454820

Title :   THE WATER-SOLUBLE POLYSACCHARIDES OF DERMATOPHYTES III. A GALACTOMANNAN FROM TRICHOPHYTON INTERDIGITALE,

Corporate Author : TEMPLE UNIV PHILADELPHIA PA SCHOOL OF MEDICINE

Personal Author(s) : Blank,F. ; Perry,M. B.

Report Date : 24 MAR 1964

Pagination or Media Count : 10

Abstract : The water-soluble polysaccharide preparation from Trichophyton interdigitale was fractionated to give two distinct galactomannans and a glucan. A galactomannan isolated via its insoluble copper complex had (alpha)D+75 degrees (water) and was composed of D-galactose (12%) and D-mannose (88%). On periodate oxidation, the galactomannan consumed 1.73 mole periodate and released 0.67 mole formic acid and 0.12 mole formaldehyde per anhydrohexose unit. Hydrolysis of the methylated galactomannan gave 2,3,5,6-tetra-O-methyl-D-galactose (1 part), 2,3,4,6-tetra-O-methyl-D-mannose (1 part), 2,3,4-tri-O-methyl-D-mannose (4 parts), and 3,4-di-O-methyl-D-mannose (2 parts). Mild acid hydrolysis of the galactomannan removed all the galactose residues, leaving a mannan having (alpha)D+84 degrees (water) whose structure was analyzed by periodate oxidation and methylation techniques. (Author)

Descriptors :   (*FUNGI, POLYSACCHARIDES), (*POLYSACCHARIDES, MOLECULAR STRUCTURE), COMPLEX COMPOUNDS, COPPER COMPOUNDS, ELECTROPHORESIS, CHROMATOGRAPHIC ANALYSIS, OPTICAL PROPERTIES, HEXOSES, ION EXCHANGE RESINS, CANADA

Distribution Statement : APPROVED FOR PUBLIC RELEASE