Accession Number : AD0456240

Title :   THE ACTION OF CARBOXYPEPTIDASES A AND B AND LEUCINE AMINOPEPTIDASE ON HORSE HEMOGLOBIN,

Corporate Author : NATIONAL RESEARCH COUNCIL OF CANADA OTTAWA (ONTARIO) DIV OF BIOSCIENCES

Personal Author(s) : Purdie,Jocelyn E. ; Smith,David B.

Report Date : 27 JUL 1964

Pagination or Media Count : 14

Abstract : Carboxypeptidase A releases histidine and tyrosine from horse oxy- and deoxy-hemoglobins; carboxypeptidase B releases arginine only. In both cases, action is more rapid with the oxygenated form. Frozen storage appears to alter the structure of hemoglobin, permitting the two enzymes together to digest further into the protein. Leucine aminopeptidase had no detectable effect on horse hemoglobin. (Author)

Descriptors :   (*PEPTIDE HYDROLASES, METABOLISM), (*HEMOGLOBIN, MOLECULAR PROPERTIES), BIOCHEMISTRY, TYROSINE, EQUINES, MOLECULAR STRUCTURE, AMINO ACIDS, PROTEINS, STORAGE, CHEMICAL REACTIONS

Distribution Statement : APPROVED FOR PUBLIC RELEASE