Accession Number : AD0466319

Title :   (NO TITLE).

Descriptive Note : Final research project rept. 31 Jul 60-30 Jul 61,

Corporate Author : WORCESTER POLYTECHNIC INST MA

Personal Author(s) : Herschman, A. ; Howe, D. W., Jr.

Report Date : 30 JUL 1961

Pagination or Media Count : 37

Abstract : The results of this investigation suggest that the use of analogue computers for the analysis of mathematical schemes for biological processes, is not only feasible but both practical and desirable. The matter of obtaining the differential equation for the various biological schemes envisaged, is straightforward and has been amply analyzed in previous reports in this series; it then becomes a matter of transferring these equations into computer circuitry -- a process which we have shown at length in this report. Once the circuits have been established, the computer may be programmed according to recipes which can be found in most manuals. The results of the computation are as accurate as the experimental evidence warrants and can be used to verify the mathematical schemes by direct comparison with such evidence. These results may also be used to analyze systems which do not lend themselves to direct intuition, showing, for example, that a given non-linear system is relatively insensitive to variation of its parameters, a result which had been assumed for purely heuristic reasons in the first part of the report and justified more extensively in the second. Finally, it is concluded that the use of these computers warrants an extension of this phase of the research to set up more complex systems. (Author)

Descriptors :   (*METABOLISM, ANALOG COMPUTERS), (*ANALOG SYSTEMS, METABOLISM), (*BIOPHYSICS, ANALOG COMPUTERS), TEMPLATES, ENZYMES, SYNTHESIS, COMPUTER LOGIC, DIFFERENTIATING CIRCUITS, FEEDBACK, INPUT OUTPUT DEVICES, DIFFERENTIAL EQUATIONS, COMPUTER PROGRAMMING, BIONICS, FEASIBILITY STUDIES, MATHEMATICAL MODELS, QUANTITATIVE ANALYSIS.

Distribution Statement : APPROVED FOR PUBLIC RELEASE