Accession Number : AD0466693

Title :   THE EFFECTS OF HIGH-INTENSITY RADIANT STIMULATION OF VARYING WAVELENGTHS AND DURATIONS ON RETINAL SENSITIVITY.

Descriptive Note : Annual progress rept. no. 2, 1 Jul 64-1 Jul 65,

Corporate Author : HONEYWELL INC ST PAUL MN

Personal Author(s) : Sidley, N. A. ; Sperling, H. G. ; Fowlks, W. L.

Report Date : 12 JUL 1965

Pagination or Media Count : 33

Abstract : The report presents a study of the effects of intense spectral stimulation on animal retinae. The study includes the use of xenon arc lamps and ruby, neodymium, and helium-neon lasers. The effects of various wavelengths, durations, and intensities of these sources are measured and assessed by three techniques: (1) Operant conditioned behavioral response to light -- this technique provides data on the time course of recovery of sensitivity to the different parts of the visible spectrum following different wavelengths, durations, and intensities of exposure; (2) Electrophysiological response of the retina to light -- by correlating the electroretinogram (ERG) with behavioral thresholds, a sensitive, rapid method is being developed to assess functional, as opposed to gross pathological, changes in the eye following intense radiation exposure; (3) Pathological-histological examination of the excised eyes -- techniques are being developed to assess the effects on the retina of light intensities which are high enough to produce longlasting reversible blindness but not high enough to burn the retina. (Author)

Descriptors :   (*RETINA, PHOTOSENSITIVITY(BIOLOGICAL)), (*PSYCHOPHYSIOLOGY, LIGHT PULSES), (*CYTOCHEMISTRY, RETINA), LASERS, THRESHOLDS(PHYSIOLOGY), PATHOLOGY, HISTOLOGY, BLINDNESS, RECOVERY, RADIATION EFFECTS, STIMULATION(PHYSIOLOGY), MONKEYS, ADAPTATION(PHYSIOLOGY), ACETYLCHOLINESTERASE, CYTOCHROME OXIDASE, SPECTRUM ANALYZERS, TIME STUDIES.

Distribution Statement : APPROVED FOR PUBLIC RELEASE