Accession Number : AD0489045

Title :   MOLECULAR SIZE OF CLOSTRIDIUM BOTULINUM TOXINS,

Corporate Author : FORT DETRICK FREDERICK MD

Personal Author(s) : Schantz, Edward J. ; Spero, Leonard

Report Date : AUG 1966

Pagination or Media Count : 10

Abstract : The molecular size of the various types of Clostridium botulinum toxins in spent culture have been estimated. The estimates were based on the rate of sedimentation of the toxin as measured by mouse assay before and after ultracentrifugation of culture. The results indicate that the molecular size of Type A toxin is the same in culture as that of the purified toxin (MW, 900,000) and that all other types, B through F, also must have molecular weights that approach that of Type A. (Author)

Descriptors :   (*CLOSTRIDIUM BOTULINUM, TOXINS AND ANTITOXINS), MOLECULAR STRUCTURE, MOLECULAR WEIGHT, CENTRIFUGES, SEDIMENTATION.

Subject Categories : Biochemistry
      Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE