Accession Number : AD0603253

Title :   STUDIES OF RESPIRATORY FUNCTION FOLLOWING THORACIC AND THORACO-ABDOMINAL INJURIES: (1) PULMONARY COMPLIANCE; (2) ALVEOLAR VENTILATION; (3) INSPIRED GAS DISTRIBUTION; (4) VENTILATION AND GAS EXCHANGE; (5) VENTILATION-PERFUSION IMBALANCE.

Descriptive Note : Final rept. for Jul 57-31 Jul 64,

Corporate Author : TULANE UNIV NEW ORLEANS LA SCHOOL OF MEDICINE

Personal Author(s) : Ziskind,Morton M. ; Creech,Oscar ,Jr.

Report Date : 31 JUL 1964

Pagination or Media Count : 36

Abstract : Observations on subjects with penetrating and blunt acute chest injuries were extended. Determinations of ventilation, arterial blood gases and pH were made. The presence of mild hyperventilation, increasedrrespiratory frequency, reduced tidal volume and increased dead space ventilation were confirmed. Carbon dioxide retention was a very uncommon finding. However, arterial oxygen unsaturation was frequent and is best explained by impaired ventilation-perfusion relationships within injured and collapsed lung. In such instances, it was often impossible to produce full oxygen saturation when the subject inspired 100 per cent oxygen. This state tended to persist and was encountered on determinations made ten to fourteen days after the original injury. Attempts to alter venous admixture by changing the position of the patient produced variable results. Twelve patients with crush injuries of the chest with flail motion of a portion of the chest wall were also studied. In this group minute ventilatory volume, respiratory frequency and dead space ventilation were usually increased. The tidal volume was low. The arterial PCO2 was usually reduced. Only one case of severe CO2 retention with a PCO2 of 85 mm.Hg. was encountered. This patient also had extensive abdominal injuries. Arterial oxygen unsaturation was the usual finding. It was impossible to produce full oxygen saturation following the administration of 100 per cent oxygen in any of the cases. (Author)

Descriptors :   (*RESPIRATION, WOUNDS AND INJURIES), (*WOUNDS AND INJURIES, RESPIRATION), SURGERY, OXYGEN, OXYGEN CONSUMPTION, CARBON DIOXIDE, MEDICAL EXAMINATION, BLOOD ANALYSIS, PH FACTOR, THERAPY, PATHOLOGY, LUNG, THORAX, ABDOMEN

Distribution Statement : APPROVED FOR PUBLIC RELEASE