Accession Number : AD0616085

Title :   TRANSPLANTATION OF NEONATAL PANCREAS IN THYMECTOMIZED HAMSTERS,

Corporate Author : NEW YORK MEDICAL COLL N Y

Personal Author(s) : House,E. L. ; Pansky,B. ; Jacobs,M. S. ; Palmer,J. ; Ostrower,V.

Report Date : 1962

Pagination or Media Count : 5

Abstract : The results of the study appear to partially substantiate Miller's conclusions concerning the role of the thymus in transplantation immunity. However, the study also points out a difference between the mouse and hamster in regard to their response to tissue grafts and to the agefunction relationship of the thymus, for Miller has indicated that the optimum effects were obtained when thymectomy was performed on the newborn. If the mice were more than two weeks old, thymectomy was ineffective in changing the reaction to transplanted tissue. At present, no attempt will be made to explain the apparent increase in islet differentiation. This phase is now under investigation. (Author)

Descriptors :   (*PANCREAS, TRANSPLANTATION), (*TRANSPLANTATION, IMMUNITY), THYMUS, EXCISION, HISTOLOGY, TISSUES(BIOLOGY), HAMSTERS, MICE, AGING(PHYSIOLOGY)

Distribution Statement : APPROVED FOR PUBLIC RELEASE