Accession Number : AD0617468

Title :   PREVENTION OF THE EMERGENCE OF ANTIBIOTICRESISTANT STRAINS OF BACTERIA BY ATABRINE,

Corporate Author : PENNSYLVANIA UNIV PHILADELPHIA SCHOOL OF MEDICINE

Personal Author(s) : Sevag,M. G.

Report Date : 16 APR 1964

Pagination or Media Count : 4

Abstract : In addition to spermine and spermidine, atabrine has been found to prevent effectively the emergence of strains resistant to streptomycin, sulfathiazole, novobiocin, erythromycin, tetracycline, penicillin, and chloramphenicol. Since atabrine already has been used widely in medical practice, we believe that it can now be incorporated into antibiotic therapy to prevent the emergence of resistant strains of bacteria. These findings are suggestive also of their possible application in early cancerous and viral systems. (Author)

Descriptors :   (*ANTIBIOTICS, CINCHONA ALKALOIDS), (*BACTERIA, SENSITIVITY), STREPTOMYCINS, TETRACYCLINES, PENICILLINS, CHLORAMPHENICOL

Distribution Statement : APPROVED FOR PUBLIC RELEASE