Accession Number : AD0617985

Title :   A DEMONSTRATION OF CODING DEGENERACY FOR LEUCINE IN THE SYNTHESIS OF PROTEIN,

Corporate Author : JOHNS HOPKINS UNIV BALTIMORE MD DEPT OF BIOPHYSICS

Personal Author(s) : Weisblum,Bernard ; Gonano,Fabio ; von Ehrenstein,Gunter ; Benzer,Seymour

Report Date : 23 DEC 1964

Pagination or Media Count : 8

Abstract : Different leucine sRNA's in E. coli are separable by countercurrent distribution. When these sRNA's are used as donors of labeled leucine during the synthesis of rabbit hemoglobin, in vitro, they distribute leucine differently into various peptides of the alpha-chain. One of the sRNA's introduces leucine only into a single position. The results indicate that there are at least two distinct codons for leucine in the amino acid code. (Author)

Descriptors :   (*PROTEINS, BIOSYNTHESIS), (*GENETICS, PROTEINS), (*AMINO ACIDS, GENETICS), (*RIBONUCLEIC ACIDS, GENETICS), NUCLEOTIDES, PEPTIDES, HEMOGLOBIN, RIBOSOMES, CHROMATOGRAPHIC ANALYSIS

Distribution Statement : APPROVED FOR PUBLIC RELEASE