Accession Number : AD0618760

Title :   PROTECTION INDUCED BY BACTERIAL ENDOTOXIN AGAINST WHOLE-BODY X-IRRADIATION IN GERMFREE AND CONVENTIONAL MICE,

Corporate Author : NOTRE DAME UNIV IND LOBUND INST

Personal Author(s) : Ledney,G. David ; Wilson,Raphael

Report Date : 04 SEP 1964

Pagination or Media Count : 4

Abstract : When conventional and germ-free mice are administered 10 micrograms of E. coli endotoxin intraperitoneally 24 hours prior to whole-body X-irradiation, the LD50(30) X-ray dose is raised to about the same degree for both groups: from 739 r to 829 r for conventional mice and 834 r to 942 r for germ-free mice. For both groups the X-ray dose-reduction factors lie in the narrow range of 1.13 to 1.15. (Author)

Descriptors :   (*TOXINS AND ANTITOXINS, RADIOPROTECTIVE AGENTS), (*RADIOPROTECTIVE AGENTS, TOXINS AND ANTITOXINS), WHOLE BODY IRRADIATION, X RAYS, ESCHERICHIA COLI, ENTEROBACTERIACEAE, IMMUNITY, RADIATION DOSAGE, LETHAL DOSAGE, MICE

Distribution Statement : APPROVED FOR PUBLIC RELEASE