Accession Number : AD0619614

Title :   WHAT IS 'NORMAL' HUMAN SERUM,

Corporate Author : KANSAS UNIV LAWRENCE DEPT OF ZOOLOGY

Personal Author(s) : Leone,Charles A. ; Jones,Ralph

Report Date : 1962

Pagination or Media Count : 6

Abstract : The distribution of the protein components in 'normal' human blood serum has been studied by paper-strip electrophoretic analysis. One hundred and four 'normal' samples, taken from donors to the Red Cross Bank of Lawrence, Kansas, were used. The average and standard deviation values for the several components were: Albumins 56.5 = 11.9 per cent; Alpha-1 Globulins 3.4 = 1.7 per cent; Alpha-2 Globulins 10.9 = 3.7 per cent; Beta Globulins 12.2 = 4.2 per cent; Gamma Globulins 17.0 = 5.8 per cent. Values are also presented for the protein content in grams per 100 ml: Albumins 4.48 = 1.2; Alpha-1 Globulins .27 = .14; Alpha-2 Globulins .85 = .32; Beta Globulins .95 = .36; Gamma Globulins 1.30 = .67. The average total protein concentration in grams per 100 ml was 7.90 = .87. Discussion is presented as to the significance of the fluctuations observed for the individual components of the sera. (Author)

Descriptors :   (*BLOOD PROTEINS, BLOOD SERUM), (*BLOOD SERUM, BLOOD PROTEINS), BLOOD CHEMISTRY, ELECTROPHORESIS, SERUM ALBUMIN, GLOBULINS, BIOCHEMISTRY, STATISTICAL TESTS, STANDARDS

Distribution Statement : APPROVED FOR PUBLIC RELEASE