Accession Number : AD0620709

Title :   A METHOD FOR THE FLUOROIMETRIC DETERMINATION OF 3-METHOXYTYRAMINE IN TISSUES AND THE OCCURENCE OF THIS AMINE IN BRAIN,

Corporate Author : GOTEBORG UNIV (SWEDEN) DEPT OF PHARMACOLOGY

Personal Author(s) : Carlsson,A. ; waldeck,B.

Report Date : 25 SEP 1963

Pagination or Media Count : 8

Abstract : A fluorimetric method for the determination of small amounts of 3-methoxytyramine, (MT), in tissues is described. After separation on ion-exchange column, MT is converted to a strongly fluorescent compound. Interference of dopamine (DA), is eliminated either by column separation or differential oxidation. MT is demonstrated in brain of some mammals indicating a role of catecholO-methyl transferase in the degradation of DA in this tissue. (Author)

Descriptors :   (*BRAIN, AMINES), (*AMINES, FLUORESCENCE), TISSUES(BIOLOGY), SEPARATION, ION EXCHANGE, OXIDATION, DECOMPOSITION, TRANSFERASES, SWEDEN

Distribution Statement : APPROVED FOR PUBLIC RELEASE