Accession Number : AD0621183

Title :   HAEMOGLOBIN H DISEASE AMONG CHINESE RESIDENTS OF TAIWAN.

Descriptive Note : Research rept.,

Corporate Author : NAVAL MEDICAL RESEARCH UNIT NO 2 TAIPEI (TAIWAN)

Personal Author(s) : Lin,Kuo Sin ; Lee,Ting-Chien ; Lu,Tsung-Cho ; Huang,Jeanette Tung-Hsiang ; Blackwell,R. Quentin

Report Date : 1965

Pagination or Media Count : 9

Abstract : Six cases of haemoglobin H disease among 5 Chinese families in Taiwan were studied. The haematological findings resembled those of previous reports and included the occurrence of the electrophoretically fast H haemoglobin component; a slight elevation in the haemoglobin F; normal amounts of haemoglobin A2; diminished red cell osmotic fragility; and the presence of red cell inclusion bodies, target cells, poikilocytosis, and reticulocytosis. The patients exhibited varying degrees of anaemia which in some cases caused little disability but which in one patient was sufficiently severe to cause death. The anaemias were microcytic and hypochromic in 4 of the 6 cases. The severity of the anaemia in the patient who died made classification difficult. The sixth case, a sister of the patient who died, had a normocytic hypochromic anaemia. (Author)

Descriptors :   (*BLOOD DISEASES, HEMOGLOBIN), (*HEMOGLOBIN, BLOOD DISEASES), ANEMIAS, HEMATOCRIT, BLOOD COUNTS, ERYTHROCYTES, LEUKOCYTES, HEMOLYSIS, HEMATOLOGY, ELECTROPHORESIS, TAIWAN

Distribution Statement : APPROVED FOR PUBLIC RELEASE