Accession Number : AD0623029

Title :   THE EFFECT OF TEMPERATURE AND PH ON THE RATE OF REACTION OF CARBON MONOXIDE AND OXYGEN WITH RED BLOOD CELLS IN NORMAL AND ANEMIC SUBJECTS, AND THE EFFECT OF HYPOXIA ON PULMONARY DIFFUSION OF CO IN NORMAL AND ANEMIC SUBJECTS.

Descriptive Note : Annual progress rept.,

Corporate Author : STATE UNIV OF NEW YORK ALBANY RESEARCH FOUNDATION

Personal Author(s) : Lawson,W. H. ,Jr.

Report Date : OCT 1965

Pagination or Media Count : 7

Abstract : The general objective of this work was to investigate physiologic adaptations and limitations of tissue oxygen delivery under stresses such as hypothermia, hypoxia, and/or exercise. Hypoxia was considered from the standpoints of low inspired O2 concentration and anemia. The methods of approach were: (A) Investigation of rates of gas exchange with red blood cells measured in vitro as a function of temperature and pH in normal and anemic subjects. (B) Investigation of the circulatory responses in pulmonary capillaries to alveolar hypoxia from the standpoint of gas diffusion for CO and pulmonary capillary blood flow.

Descriptors :   (*ANEMIAS, RESPIRATION), (*HYPOXIA, BLOOD CIRCULATION), TEMPERATURE, PH FACTOR, CARBON COMPOUNDS, MONOXIDES, OXYGEN CONSUMPTION, ERYTHROCYTES, LUNG, TISSUES(BIOLOGY), ADAPTATION(PHYSIOLOGY), STRESS(PHYSIOLOGY), HYPOTHERMIA, EXERCISE(PHYSIOLOGY), REACTION KINETICS

Distribution Statement : APPROVED FOR PUBLIC RELEASE