Accession Number : AD0623378

Title :   ELECTROCORTICAL CORRELATES OF AVOIDANCE CONDITIONING IN THE MONKEY AND THEIR MODIFICATIONS WITH ATROPINE AND AMPHETAMINE,

Corporate Author : PISA UNIV (ITALY) ISTITUTO DI FARMACOLOGIA

Personal Author(s) : Ricci,G. F. ; Zamparo,L.

Report Date : 1965

Pagination or Media Count : 17

Abstract : The results of the experiments indicate that in the monkey the impairment of the acquisition and of the retention of a conditioned avoidance response caused by atropine is related to the changes of electrocortical activity and of cortical excitability caused by the drug. The impairment of behaviour and the modifications of the cortical evoked responses induced by this anticholinergic drug are, however, effectively counteracted by enhancing the activity of the adrenergic system by means of amphetamine, while the effects of the EEG rhythms caused by atropine are not modified.

Descriptors :   (*CONDITIONED RESPONSE, CEREBRAL CORTEX), (*ATROPINE, ELECTROENCEPHALOGRAPHY), (*AMPHETAMINES, ELECTROENCEPHALOGRAPHY), (*ELECTROENCEPHALOGRAPHY, CONDITIONED RESPONSE), BEHAVIOR, CENTRAL NERVOUS SYSTEM, MOTOR REACTIONS, PARASYMPATHOLYTIC AGENTS, PARASYMPATHOMIMETIC AGENTS, SYMPATHOLYTIC AGENTS, MONKEYS

Distribution Statement : APPROVED FOR PUBLIC RELEASE