Accession Number : AD0623981

Title :   HYDROGELS OF POLY(HYDROXYETHYL METHACRYLATE) AND HYDROXYETHYL METHACRYLATE - GLYCEROL MONO-METHACRYLATE COPOLYMERS,

Corporate Author : CEDARS-SINAI MEDICAL CENTER LOS ANGELES CALIF POLYMER DIV

Personal Author(s) : Yasuda,H. ; Gochin,Michael ; Stone,William ,Jr.

Report Date : 1965

Pagination or Media Count : 29

Abstract : Hydrophilic three dimensional polymer networks (hydrogels) were prepared from hydroxyethyl methacrylate and copolymer of HEMA and glycerol monomethacrylate. The equilibrium water content of the hydrogels in water was investigated as a function of the initial dilution of the polymerization mixture, the type of solvent, and the hydrophilicity of the polymer. The initial dilution was found to have a decisive effect on the swelling or deswelling of hydrogels after the completion of the gel formation. With relatively less hydrophilic hydrogels, there is a critical initial dilution to produce the gel which does not swell or deswell in water after the gel formation. This 'iso-volumic' initial dilution shifts toward a higher dilution as the hydrophilicity of the hydrogels increases; however, when hydrophilicity of the polymer rises above a certain point, gels always swell in water. Permeability of oxygen through hydrogels was also studied. (Author)

Descriptors :   (*PROSTHETICS, POLYMERS), (*GELS, SCIENTIFIC RESEARCH), (*ACRYLIC RESINS, GELS), (*MEMBRANES, GELS), MEMBRANES, POLYMERIZATION, HYDRATES, OPTICAL PROPERTIES, SOLVENTS, WATER, GLYCOLS, OPHTHALMOLOGY, EYE

Subject Categories : Medicine and Medical Research
      Physical Chemistry
      Polymer Chemistry
      Plastics

Distribution Statement : APPROVED FOR PUBLIC RELEASE