Accession Number : AD0625410

Title :   SPIKE PROBABILITIES IN NEURONES: INFLUENCE OF TEMPORAL STRUCTURE IN THE TRAIN OF SYNAPTIC EVENTS,

Corporate Author : RAND CORP SANTA MONICA CALIF

Personal Author(s) : Segundo,Jose P. ; Perkel,Donald H. ; Moore,George P.

Report Date : DEC 1965

Pagination or Media Count : 79

Abstract : Certain input-output relations were studied by way of intraneuronal recordings in isolated visceral ganglia of Aplysia californica. All cells exhibited a prolonged sequence of excitatory postsynaptic potentials (EPSP's) of a single type and, as a consequence, produced recurrent spikes. EPSP's either (1) occurred 'spontaneously' or (2) were initiated by stimulating a connective with shocks from a stimulator driven by a Geiger counter. The prespike epoch was analyzed and the events that trigger the postsynaptic spike were identified in a probabilistic manner. Experiments in digital-computer-simulated neurons reproduced and extended the results of animal experiments.

Descriptors :   (*NERVE IMPULSES, PROBABILITY), TIME, STATISTICAL ANALYSIS, NERVE CELLS, BIONICS, GANGLIA, CYBERNETICS, DIGITAL COMPUTERS

Subject Categories : Medicine and Medical Research
      Bionics

Distribution Statement : APPROVED FOR PUBLIC RELEASE