Accession Number : AD0625953

Title :   NATURAL DRUG RESISTANCE OF HETEROGENEOUS SINGLE CELL TRANSPLANTS.

Descriptive Note : Semi-annual rept. on J-202, 17 Sep 64-16 Mar 65,

Corporate Author : SASAKI FOUNDATION MEDICAL INSTITUTION TOKYO (JAPAN)

Personal Author(s) : Yoshida,Tomizo

Report Date : 16 MAR 1965

Pagination or Media Count : 4

Abstract : The present study attempts to demonstrate precisely the following points: (a) whether cellular constitution of a clonal cancer cell population is uniform as regards the degree of natural drug resistance; (b) whether the degree of drug resistance of cancer clone fluctuates during animal passages; and (c) whether any correlation is found between the degree of drug resistance and chromosonal constitution of cells in a cancer clone. The drug resistance under question in this case is not acquired but natural one.

Descriptors :   (*CANCER, DRUGS), (*DRUGS, RESISTANCE(BIOLOGY)), TRANSPLANTATION, CELLS(BIOLOGY), CHROMOSOMES, JAPAN

Subject Categories : Medicine and Medical Research
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE