Accession Number : AD0631036

Title :   RECOMBINATION OF A POOL OF DNA FRAGMENTS WITH COMPLEMENTARY SINGLE-CHAIN ENDS.

Descriptive Note : Technical rept.,

Corporate Author : JOHNS HOPKINS UNIV BALTIMORE MD DEPT OF STATISTICS

Personal Author(s) : Watson,G. S. ; Smith,W. K. ; Thomas,C. A.

Report Date : 1966

Pagination or Media Count : 10

Abstract : A model for Gentic Recombination in bacteriophage is presented. The DNA molecules in the pool are broken into fragments randomly, enzymes attack the 3'-ends of the fragments, the exposed bases seek complementary sequences on other fragments and new molecules are reassembled. Formulae are given for the ratio of output to input molecules and for the recombination rate and the length of the genetic map. (Author)

Descriptors :   (*BACTERIOPHAGES, *GENETICS), (*DEOXYRIBONUCLEIC ACIDS, RECOMBINATION REACTIONS), GENES, MOLECULAR PROPERTIES, ENZYMES, NUCLEOTIDES, MATHEMATICAL MODELS

Subject Categories : Biochemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE