Accession Number : AD0631926

Title :   TECHNICAL REPORT COVERING THE PERIOD 1 JUNE 1957 - 31 MAY 1959,

Corporate Author : LIEGE UNIV (BELGIUM) INSTITUT DE THERAPEUTIQUE EXPERIMENTALE

Personal Author(s) : Dallemagne,M. J.

Report Date : 31 MAY 1959

Pagination or Media Count : 74

Abstract : Calcium, phosphorus and carbon isotope studies were made on biological and synthetic phosphates to compare the behaviour of these materials. Special attention was paid to remodelling of crystals. The high exchange values obtained for calcium exchange were reconsidered and interpreted. The mechanism of remodelling is discussed. Phosphorus exchange was also studied in total and mineralized bone. Labelled C02 exchange in bone and teeth give the demonstration that C02 is located in the bulk of the crystals but this location seems to depend on recrystallization phenomena. Physicochemical studies were performed on synthetic phosphates and bone or teeth mineral. When synthetic phosphates with various Ca/P ratios are treated by the methods used for the destruction of the organic phase of bone, the Ca/P ratio raises up to 2.14. Special attention was paid to the phonomenon called peptization of bone mineral. The influence of different factors which induce peptization was studied. Autoradiographic studies on bone slices were made: total bone and mineralized bone slices do not behave in a similar manner when suspended in vitro in a tagged calcium solution. Hot spots only appear when total bone is concerned. The signification of the classical autoradiographic picture obtained in vitro with total bone slices is discussed. Phosphorus behaves just like calcium and other compounds which are not present in bone are also located in hot spots. (Author)

Descriptors :   (*BONES, PHOSPHATES), (*TEETH, PHOSPHATES), (*AUTORADIOGRAPHY, BONES), (*PHOSPHATES, INFRARED SPECTROSCOPY), DENTISTRY, CALCIFICATION, CRYSTAL STRUCTURE, CRYSTAL GROWTH, CALCIUM, SALTS, CARBON, CARBONATES, CARBON DIOXIDE, PHOSPHORUS, LABELED SUBSTANCES, RADIOACTIVE ISOTOPES, RECRYSTALLIZATION, IN VITRO ANALYSIS, IN VIVO ANALYSIS, X RAY DIFFRACTION, DIFFUSION, MAGNESIUM, FLUORINE, EXPERIMENTAL DATA, BELGIUM

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE