Accession Number : AD0632874

Title :   LA SUPPRESSION DES DIFFERENTS ETATS DE SOMMEIL (SUPPRESSION OF DIFFERENT SLEEP STATES).

Descriptive Note : Scientific rept.,

Corporate Author : LYON UNIV (FRANCE) LABORATOIRE DE PATHOLOGIE EXPERIMENTALE

Personal Author(s) : Vimont-Vicary,Pierre

Report Date : 1965

Pagination or Media Count : 99

Abstract : Cats with chronically implanted electrodes were selectively deprived of paradoxical sleep for 1-26 days by the swimming pool and electric shock techniques. The 'need for paradoxical sleep' was demonstrated by the progressive diminution of the intervals between attempts to enter this phase. Deprivation of this phase of sleep for more than a week produced somnolence, muscular hypotony, sexual excitement, tachycardia, and a picture resembling hallucinations. At the end of this deprivation there was a selective paradoxical sleep 'rebound,' and up to 60% of the first 6 hours was spent in this phase of sleep. Substances with an inhibitory effect on paradoxical sleep, such as atropine, monoamine oxidase inhibitors, and reserpine, were studied, and the results are discussed in light of a neurohumoral hypothesis of sleep. (Author)

Descriptors :   (*SLEEP, INHIBITION), PHYSIOLOGY, ELECTROENCEPHALOGRAPHY, ATROPINE, ENZYME INHIBITORS, RESERPINE, CATS, FRANCE

Subject Categories : Anatomy and Physiology
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE