Accession Number : AD0633119

Title :   EFFECTS OF PREDNISOLONE AND TRIAMCINOLONE ON CORTICOSTEROID LEVELS IN PAROTID FLUID, SERUM, AND URINE.

Descriptive Note : Rept. for Jun 65-Jan 66,

Corporate Author : SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX

Personal Author(s) : Jenson,Robert L. ; Shannon,Ira L.

Report Date : MAR 1966

Pagination or Media Count : 16

Abstract : A simultaneous determination was made of 17-OHCS in serum, urine, and parotid fluid, by the Porter-Silber reaction, after the oral administration of prednisolone, triamcinolone, or placebo to 240 normal human subjects. The data clearly demonstrate the homology of serum and parotid fluid 17-OHCS levels through a range of 0.22 micrograms to 57.72 micrograms/100 m1. in serum. Urinary excretion of steroids was highest following prednisolone, intermediate in the placebo group, and lowest after triamcinolone dosage. (Author)

Descriptors :   (*CORTICOSTEROID AGENTS, SECRETION), SALIVA, BLOOD SERUM, URINE, DOSAGE, EXCRETION

Subject Categories : Anatomy and Physiology
      Medicine and Medical Research
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE