Accession Number : AD0633742

Title :   PREPARATION OF POTENTIAL ANTIMALARIAL COMPOUNDS.

Descriptive Note : Final rept. 1 Jul-15 Nov 65,

Corporate Author : PENINSULAR CHEMRESEARCH INC GAINESVILLE FLA

Personal Author(s) : Warner,Dale A.

Report Date : MAY 1966

Pagination or Media Count : 21

Abstract : Satisfactory procedures were developed and samples were prepared of the following compounds: chloroacetone oxime, 1,4-bis(2-oximinopropyl)piperazine, 1,4-bis(2(7-chloro-4-quinolyamino)propyl) piperazine, 3,5-bis(1-pyrrolidinomethyl)-4-hydroxyacetanilide, and 3,5-bis(1-pyrrolidinomethyl)-4-hydroxyaniline hydrochloride. Work was stopped before the preparation of 2,6-bis(1-pyrrolidinomethyl)-4-(7-chloro-4-quinolylamino)phenol could be demonstrated. (Author)

Descriptors :   (*ANTIMALARIALS, SYNTHESIS(CHEMISTRY)), (*ORGANIC NITROGEN COMPOUNDS, ANTIMALARIALS), OXIMES, CHLORINE COMPOUNDS, ACETONES, NITROGEN HETEROCYCLIC COMPOUNDS, PYRROLES, AMINES, QUINOLINES, PREPARATION

Subject Categories : Pharmacology
      Organic Chemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE