Accession Number : AD0634519

Title :   CATECHOL AMINE MEASUREMENTS ASSOCIATED WITH AUTONOMIC-LABYRINTHINE RESPONSES IN MAN EXPOSED TO POSITIVE (+GZ) ACCELERATION.

Descriptive Note : Final rept.,

Corporate Author : NAVAL AIR DEVELOPMENT CENTER JOHNSVILLE PA AEROSPACE MEDICAL RESEARCH DEPT

Personal Author(s) : York, Elihu ; brown,Kenneth R. ; Goldfien,Aalan

Report Date : 13 APR 1966

Pagination or Media Count : 18

Abstract : Five normal subjects and two labyrinthine-defective subjects were exposed to acceleration profiles consisting of linear, angular and combined (linear plus angular) stress. Catechol amines were measured in plasma and urine for both groups. A demonstrated rise in plasma nor-epinephrine occurred in two of the five normal subjects, both of whom developed motion sickness following a 'combined' acceleration stress. The normal group had measurable plasma epinephrine levels, under most circumstances, whereas the labyrinthine defective group had none. Although there is insufficient data to make a clear-cut separation between different types of acceleration stress in the two groups, and their associated biochemical responses; nevertheless, there is some evidence to suggest that the intact labyrinth is a factor influencing elaboration of catechol amines, which in turn may be implicated in the development of motion sickness. (Author)

Descriptors :   (*ACCELERATION TOLERANCE, *AMINES), (*EPINEPHRINE, EXCRETION), MOTION SICKNESS, VESTIBULAR APPARATUS, STRESS(PHYSIOLOGY), BLOOD PLASMA, URINE, MEASUREMENT

Subject Categories : Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE