Accession Number : AD0636712
Title : THE N-ALKYL ALPHA CYANOACRYLATE TISSUE ADHESIVES.
Descriptive Note : Technical rept.
Corporate Author : WALTER REED ARMY MEDICAL CENTER WASHINGTON D C ARMY MEDICAL BIOMECHANICAL RESEARCH LAB
Personal Author(s) : Leonard, Fred
Report Date : MAY 1966
Pagination or Media Count : 20
Abstract : A summary is given of studies directed toward the development of biologically receptive adhesives to be used as hemostasis inducing compounds and tissue adhesives in nonsuture closure of wounds. In addition to the usually delineated attributes of polymers for implant use, such as nontoxicity, non-allergenicity, etc., a tissue adhesive, ideally should (1) wet and spread on the tissue substrate, (2) polymerize rapidly and form a polymeric film (preferably a flexible one) which coats the tissue substrate, and (3) be biodegradable. The n-alkyl alpha cyanoacrylates fulfill these requirements to varying degrees.
Descriptors : (*SURGICAL SUPPLIES, ADHESIVES), (*TISSUES(BIOLOGY), *ADHESIVES), (*ACRYLIC RESINS, ADHESIVES), NITRILES, POLYMERIZATION, DEGRADATION
Subject Categories : Medical Facilities, Equipment and Supplies
Adhesives, Seals and Binders
Distribution Statement : APPROVED FOR PUBLIC RELEASE