Accession Number : AD0636712

Title :   THE N-ALKYL ALPHA CYANOACRYLATE TISSUE ADHESIVES.

Descriptive Note : Technical rept.

Corporate Author : WALTER REED ARMY MEDICAL CENTER WASHINGTON D C ARMY MEDICAL BIOMECHANICAL RESEARCH LAB

Personal Author(s) : Leonard, Fred

Report Date : MAY 1966

Pagination or Media Count : 20

Abstract : A summary is given of studies directed toward the development of biologically receptive adhesives to be used as hemostasis inducing compounds and tissue adhesives in nonsuture closure of wounds. In addition to the usually delineated attributes of polymers for implant use, such as nontoxicity, non-allergenicity, etc., a tissue adhesive, ideally should (1) wet and spread on the tissue substrate, (2) polymerize rapidly and form a polymeric film (preferably a flexible one) which coats the tissue substrate, and (3) be biodegradable. The n-alkyl alpha cyanoacrylates fulfill these requirements to varying degrees.

Descriptors :   (*SURGICAL SUPPLIES, ADHESIVES), (*TISSUES(BIOLOGY), *ADHESIVES), (*ACRYLIC RESINS, ADHESIVES), NITRILES, POLYMERIZATION, DEGRADATION

Subject Categories : Medical Facilities, Equipment and Supplies
      Adhesives, Seals and Binders

Distribution Statement : APPROVED FOR PUBLIC RELEASE