Accession Number : AD0637583

Title :   EFFECTS OF SIMULATED HIGH ALTITUDE ON LEFT CIRCUMFLEX CORONARY FLOW, BLOOD PRESSURE, CARDIAC OUTPUT, AND MYOCARDIAL METABOLISM IN THE UNMEDICATED GREYHOUND DOG.

Corporate Author : NAVAL AEROSPACE MEDICAL INST PENSACOLA FLA

Personal Author(s) : Wirthlin,LeRoy S. ; Beck,E. Peter

Report Date : 18 MAY 1966

Pagination or Media Count : 28

Abstract : The effects of simulated high altitudes on phasic coronary artery flow, central aortic pressure and flow, and myocardial metabolism were studied in unmedicated greyhound dogs 1-2 weeks after implantation of sensing devices. The adaptation of coronary flow to hypoxia was medicated through an increase in heart rate, coronary vasodilation, and increase in mean pressure. Coronary sinus pO2 was found to correlate highly with arterial pO2. The linear relationship of coronary flow to oxygen usage persisted during hypoxia. Mayer waves with rhythmic fluctuations in coronary flow were encountered. (Author)

Descriptors :   (*CARDIOVASCULAR SYSTEM, *HYPOXIA), (*BLOOD CIRCULATION, HYPOXIA), HIGH ALTITUDE, SIMULATION, HEART, METABOLISM, BLOOD PRESSURE, BLOOD VOLUME, ADAPTATION(PHYSIOLOGY), OXYGEN, DOGS

Subject Categories : Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE